What it is
- Prolotherapy: a solution is injected at the points where ligaments or tendons attach to bone, sometimes over a few sessions
- Why they are used: both are thought to help the body's own healing response, but how well they work is still being studied
- Who is not suitable: people with some blood disorders, active infection, certain cancers, or who take some blood-thinning medicines
Who should see a doctor
Signs to get checked
- Long-standing knee, tendon or ligament pain not improving with exercise and other treatment
- Anyone who has been advised PRP or prolotherapy elsewhere and wants a second opinion
- Anyone wanting to understand the options before deciding
What happens at Rehabify
- 01
Review of scans
To see whether the problem is one where these injections may be considered.
- 02
Discussion
The doctor explains the evidence, possible benefits, risks, costs and other options, so you can decide.
- 03
Procedure if chosen
Done with clean technique and, where needed, image guidance. Written consent is taken.
- 04
Rehab
Exercise continues before and after, as this is the main treatment.
The doctor decides whether the procedure is suitable for you after examining you.
Before and after your visit
How to prepare
- Bring scans, reports and a list of medicines, including blood thinners and painkillers
- Ask the doctor which medicines to stop before the procedure; do not stop any on your own
- Eat normally and drink water on the day
- Plan to rest the area for a day or two afterwards
After your visit
Some soreness for a few days is common. You can send questions on WhatsApp between visits.
When to get help urgently
Common questions
Does PRP regrow cartilage in the knee?
There is no good evidence that it regrows cartilage. Some people report less pain for a time. The doctor will explain what to expect.
Is PRP better than a steroid injection?
Studies give mixed results. Steroids tend to act faster but for a shorter time. The choice depends on your problem and preferences.
How many injections are needed?
It varies. Some plans use one PRP injection, others a short course. Prolotherapy is often given over several sessions.
Is it safe?
PRP uses your own blood, so allergic reactions are rare. Risks include pain, swelling, bruising and, rarely, infection.
Will I still need exercise?
Yes. Exercise remains the main treatment for joint and tendon pain. Injections, if used, support rehab rather than replace it.
Sources
- [1]
American College of Rheumatology (ACR) and Arthritis Foundation guideline for osteoarthritis of the hand. hip and knee, 2019 (recommends against PRP for knee osteoarthritis)
- [2]
National Institute for Health and Care Excellence (NICE) interventional procedures guidance IPG637. Platelet-rich plasma injections for knee osteoarthritis
- [3]
American Academy of Orthopaedic Surgeons (AAOS) clinical practice guideline. Management of osteoarthritis of the knee (non-arthroplasty)
This page is for general education and does not replace a consultation. The right plan depends on your examination.

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